In the summer of 2023, Joe Manganiello and Sofia Vergara split up and filed for divorce. Rumors spread like wildfire about the “reasons” for the divorce, and one of the biggest rumors was that Sofia simply didn’t want to have another child and Joe wanted to be a father. Sofia even referenced that issue in post-divorce interviews, and I thought it was probably the root of their split. But now Joe has written a memoir called Bloodlines, and he talks about the catastrophic autoimmune illness he dealt with for years, including the years he was married to Sofia. According to Joe, the real story is that Sofia had no interest in being tied to a man in poor health, and she even mocked and criticized him at his lowest.
Joe Manganiello‘s long hair is tied up in a top knot, his beard is perfectly groomed, and his skin boasts glowing tan. He looks healthy because, finally, he is. For seven of the last 10 years, the actor was secretly fighting a mysterious autoimmune illness so virulent it nearly killed him. In his new memoir Bloodlines (out Oct. 13), Manganiello, 49, opens up about recovering from a health battle that led to “major organ amputation” and contributed to the end of his seven-year marriage to actress Sofía Vergara, 54: “I can’t believe I’m alive,” he says. “I feel like I was reborn.”
Over the course of seven years, Manganiello lost 60 lbs., underwent countless colonoscopies, and in one emergency surgery in 2016, had part of his intestines removed, leaving him unable to go to the bathroom normally and relying on an ostomy bag.
Manganiello was prescribed meds for nerve pain as well as drugs used to treat Crohn’s and colitis. “None of them worked on me,” he says. Forced to turn to hydrocodone pills, fentanyl patches and marijuana to ease his agony, Manganiello wrestled with his hard-won 13 years of sobriety. “I didn’t feel like I deserved to say that I was sober,” he recalls, “[but] I had to put the pain and the condition first.”
As Manganiello cycled through hospitals searching for answers, his illness took a toll on his marriage, which he writes had “become devoid of any emotionality whatsoever.” He claims in the book that Vergara refused to hug him even when he begged and that she ridiculed him for his 5-lb. chihuahua Bubbles, a then-sickly pup Manganiello had adopted in 2019 when he was considering suicide. “I had to give my gun away because I kept thinking about it, and then the dog came. I went from being the patient to the caretaker,” he says.
The couple’s dream of having a child together had also been dashed. Vergara would later tell a Spanish newspaper that their marriage “broke up because my husband was younger; he wanted to have kids, and I didn’t want to be an old mom.” But Manganiello says he gave up the idea because of his illness. After failed IVF attempts led to them considering egg donors, he says he didn’t want to die and leave Vergara with a child “who wasn’t biologically hers.”
Writing this book was his way of correcting the record: “There were things said and printed about me that were false,” he says.
His marriage crumbling and his body failing, Manganiello looked beyond traditional medicine for answers. At one point his desperate search brought him to Cuba where a medicine man had him lick the pituitary gland in a goat’s skull, but Manganiello believes he eventually found healing through a Santa Monica shaman, who told him generational trauma was to blame.
Manganiello’s great-grandmother lost nine of her children to genocide in Armenia, and his grandmother battled lupus. He says he unburdened himself of his family’s torment by confronting it: “Whatever chains there were to the past suffering of my ancestors, they were completely broken. There’s not an ounce of fear in me about moving forward with my life.”
Wow, so even the story about the dog was false? In 2023, people made a big deal about how Bubbles Manganiello, the Chihuahua, was Sofia’s dog and she gave the dog to Joe in the divorce because Bubbles clearly favored Joe. Now it turns out that Bubbles was always Joe’s dog, and Bubbles probably had good reason to hate Sofia? Yikes. Mostly, I’m stunned by how good Vergara’s PR really is – she really got her side out immediately, and I believed that they split due to Joe’s desire to start a family. We had no idea that Joe’s health was struggling to this extent, nor did we know that Sofia seemingly checked out of the marriage as soon as he got sick (women in male-dominated fields).
Photos courtesy of Cover Images, Avalon Red.
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, Los Angeles, CA -20200106 – The 77th Annual Golden Globe Awards – Arrivals, at The Beverly Hilton
-PICTURED: Joe Manganiello, Sofia Vergara
-PHOTO by: Sara De Boer/startraksphoto.comThis is an editorial, rights-managed image. Please contact Startraks Photo for licensing fee and rights information at sales@startraksphoto.com or call +1 212 414 9464 This image may not be published in any way that is, or might be deemed to be, defamatory, libelous, pornographic, or obscene. Please consult our sales department for any clarification needed prior to publication and use. Startraks Photo reserves the right to pursue unauthorized users of this material. If you are in violation of our intellectual property rights or copyright you may be liable for damages, loss of income, any profits you derive from the unauthorized use of this material and, where appropriate, the cost of collection and/or any statutory damages awarded
Featuring: Joe Manganiello, Sofia Vergara
Where: Los Angeles, California, United States
When: 05 Jan 2020
Credit: Sara De Boer/startraksphoto.com
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Joe Manganiello, Sofia Vergara attends the 77th Annual Golden Globe Awards at The Beverly Hilton Hotel on January 05, 2020 in Beverly Hills, California
© Jill Johnson/jpistudios.com,Image: 562855812, License: Rights-managed, Restrictions: , Model Release: no, Credit line: jpistudios.com / JPI Studios / Avalon
- Joe Manganiello and Sofia Vergara arrive at the 2020 Vanity Fair Oscar Party held at the Wallis Annenberg Center for the Performing Arts on February 9, 2020 in Beverly Hills, Los Angeles, California, United States.,Image: 563481602, License: Rights-managed, Restrictions: WORLD RIGHTS – Fee Payable Upon Reproduction – For queries contact Avalon.red – sales@avalon.red London: +44 (0) 20 7421 6000 Los Angeles: +1 (310) 822 0419 Berlin: +49 (0) 30 76 212 251, Model Release: no, Credit line: Xavier Collin / Image Press Agency / Avalon
- WEST HOLLYWOOD, LOS ANGELES, CALIFORNIA, USA – JUNE 28: American actor Joe Manganiello arrives at the Los Angeles Premiere Of AMC+’s Original Series ‘Moonhaven’ held at the The London Hotel West Hollywood at Beverly Hills on June 28, 2022 in West Hollywood, Los Angeles, California, United States.,Image: 703713068, License: Rights-managed, Restrictions: , Model Release: no, Pictured: Joe Manganiello, Credit line: Xavier Collin / Image Press Agency / Avalon
- WEST HOLLYWOOD, CA – JUNE 28: Joe Manganiello attends AMC+ Original Series “Moonhaven” Premiere Event at The London West Hollywood at Beverly Hills on June 28, 2022 in West Hollywood, California.,Image: 703766430, License: Rights-managed, Restrictions: , Model Release: no, Pictured: Joe Manganiello, Credit line: Jeffrey Mayer / Avalon
- Joe Manganiello, Sofia Vergara attends the 2023 Vanity Fair Oscar Party Celebrating the 95th Annual Academy Awards Hosted By Radhika Jones at Wallis Annenberg Center for the Performing Arts on March 12, 2023 in Beverly Hills, California,Image: 762353074, License: Rights-managed, Restrictions: , Model Release: no, Pictured: Joe Manganiello, Sofia Vergara, Credit line: – / JPI Studios / Avalon
- Joe Manganiello bei der Vanity Fair Oscar Party 2023 anlässlich der 95. Oscar-Verleihung im Wallis Annenberg Center for the Performing Arts. Beverly Hills, 12.03.2023 *** Joe Manganiello at the Vanity Fair Oscar Party 2023 celebrating the 95 Academy Awards at the Wallis Annenberg Center for the Performing Arts Beverly Hills, 12 03 2023. Foto:xD.,Image: 812192011, License: Rights-managed, Restrictions: imago is entitled to issue a simple usage license at the time of provision. Personality and trademark rights as well as copyright laws regarding art-works shown must be observed. Commercial use at your own risk., Model Release: no, Credit line: IMAGO/Dave Bedrosian / Avalon
- LOS ANGELES, CA – JANUARY 6: Caitlin O Connor, Joe Manganiello at The Art of ElysiumĂ•s 2024 Heaven Gala at The Wiltern Theater in Los Angeles, California on January 6, 2024. Copyright: xFayexSadoux,Image: 834982177, License: Rights-managed, Restrictions: imago is entitled to issue a simple usage license at the time of provision. Personality and trademark rights as well as copyright laws regarding art-works shown must be observed. Commercial use at your own risk., Model Release: no, Credit line: IMAGO/Faye Sadou / Avalon
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– Los Angeles, USA -20220628-
Los Angeles Premiere Of `Moonhaven`.
-PICTURED: SofÃa Vergara, Joe Manganiello
-PHOTO by: Faye`s Vision/Cover Images/INSTARimages.com
-51735590.jpgThis is an editorial, rights-managed image. Please contact Instar Images LLC for licensing fee and rights information at sales@instarimages.com or call +1 212 414 0207 This image may not be published in any way that is, or might be deemed to be, defamatory, libelous, pornographic, or obscene. Please consult our sales department for any clarification needed prior to publication and use. Instar Images LLC reserves the right to pursue unauthorized users of this material. If you are in violation of our intellectual property rights or copyright you may be liable for damages, loss of income, any profits you derive from the unauthorized use of this material and, where appropriate, the cost of collection and/or any statutory damages awarded
Featuring: Sofia Vergara, Joe Manganiello
Where: Los Angeles, California, United States
When: 28 Jun 2022
Credit: Faye`s Vision/Cover Images/INSTA










